CytoMed Expands Research Collaboration Into China After Entering Into MOU With China-Based Hangzhou CNK Therapeutics Co., Ltd.

Author: Happy Mohamed | August 29, 2023 09:10am

 CytoMed Therapeutics Limited (NASDAQ:GDTC) ("CytoMed" or "the Company"), a Singapore biopharmaceutical company focused on utilizing its licensed proprietary tech to create novel allogeneic cell-based immunotherapies for treating a range of cancers, recently announced entering into a Memorandum of Understanding (MOU) with China-based Hangzhou CNK Therapeutics Co., Ltd. (CNK). Under the terms of the agreement, CytoMed will be able to utilize CNK's PiggyBac technology to permanently graft the Chimeric Antigen Receptor (CAR) gene directly into its patented gamma delta T-cells through a non-viral gene editing method.

"We are currently using mRNA technology whereby the CAR gene is transient, and hence, the CAR expression would cease after a period of time, leaving non-CAR γδ T cells in the patient's body," said Dr. Tan Wee Kiat, Chief Operating Officer of CytoMed. "The γδ T cells that remain continue to be cytotoxic with the ability to kill cancer cells. Leveraging CNK's technology, the CAR gene now would be expressed for as long as the γδ T cells are present in the body. This means that the CAR-γδ T cells can now exert a targeted attack for as long as it is present in the patient's body, potentially increasing the efficacy of our CAR γδ T cells in the patient."

The MOU will have an initial duration of one-year, with an option to renew and remains subject to definitive agreements and other customary closing conditions. In addition, there remains a possibility for CytoMed and CNK to engage in a joint venture to conduct clinical trials within China.

For more information about the company's services, latest news, and ongoing initiatives, visit https://w2.cytomed.sg and https://spotlightgrowth.com/singapores-leap-into-the-future-of-cell-and-gene-therapies/

Posted In: GDTC