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News

Health Canada Authorizes RYBREVANT In Combination With Carboplatin And Pemetrexed As The Only Targeted First-Line Treatment Approved For Patients With Non-Small Cell Lung Cancer With EGFR Exon 20 Insertion Mutations

Author: Benzinga Newsdesk | July 03, 2024 08:04am

Phase 3 PAPILLON study showed RYBREVANT® in combination with carboplatin and pemetrexed significantly improved progression-free survival, reducing the risk of disease progression or death by 60 per cent versus carboplatin and pemetrexed alone in patients with previously untreated NSCLC with EGFR exon 20 insertion mutations.1

TORONTO, July 3, 2024 /CNW/ - Johnson & Johnson (NYSE: JNJ) announced today that Health Canada, through a Priority Review, has issued a Notice of Compliance (NOC) for RYBREVANT® (amivantamab) in combination with platinum-based chemotherapy (carboplatin and pemetrexed) for the first-line treatment of adult patients with locally advanced (not amenable to curative therapy) or metastatic non-small cell lung cancer (NSCLC) with activating epidermal growth factor receptor (EGFR) Exon 20 insertion mutations.1 


 

Posted In: JNJ