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Monday, IDEAYA Biosciences Inc (NASDAQ:IDYA) released clinical data for the IDE397 Phase 2 monotherapy expansion dose in methylthioadenosine phosphorylase-deletion urothelial and non-small cell lung cancer patients (NSCLC).
“IDE397 is a potential first-in-class MAT2A inhibitor, that is being advanced as a monotherapy agent in priority MTAP-deletion solid tumor types and in high conviction rational combinations, including with Amgen’s investigational MTA-cooperative protein arginine methytranferase 5 inhibitor AMG 193 in NSCLC and with Gilead’s Trop-2 directed anti-body conjugate Trodelvy in urothelial cancer,” said Yujiro S. Hata, Chief Executive Officer and Founder, IDEAYA Biosciences.
“The IDE397 clinical data update demonstrates important clinical proof-of-concept in MTAP-deletion solid tumors to deliver RECIST responses and encouraging preliminary durability, with a convenient 30mg once-a-day tablet and favorable adverse event profile.”
The clinical data update in the eighteen (18) evaluable patients includes:
Price Action: IDYA shares are up 15.2% at $39.45 at last check Monday.
Image by PDPics from Pixabay
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Posted In: IDYA