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NEW YORK, Aug. 02, 2024 (GLOBE NEWSWIRE) -- Tourmaline Bio, Inc. (Tourmaline) (NASDAQ:TRML), a late-stage clinical biotechnology company developing transformative medicines to dramatically improve the lives of patients with life-altering immune and inflammatory diseases, today presented a poster at the American Society of Preventive Cardiology (ASPC) Congress in Salt Lake City, Utah, detailing the rationale and design of the company's TRANQUILITY Phase 2 study examining the potential of its lead candidate, TOUR006, to reduce high-sensitivity C-reactive protein (hs-CRP), a key biomarker of residual inflammatory cardiovascular risk, in patients with chronic kidney disease (CKD) and elevated hs-CRP.
Patients with CKD and elevated hs-CRP are at heightened risk of atherosclerotic cardiovascular disease (ASCVD), including heart attack, stroke, and peripheral artery disease, despite current standard-of-care treatments. The IL-6 pathway has been identified as a significant contributor to ASCVD risk, particularly in CKD patients. TOUR006 has previously shown promise in reducing hs-CRP levels in patients with inflammatory autoimmune diseases.
Posted In: TRML