Elevation Oncology Reports Initial Data From Dose Escalation Portion Of Ongoing Phase 1 Clinical Trial Of EO-3021; 42.8% Confirmed ORR Observed In Claudin 18.2-enriched Subset Of Gastric And GEJ Cancer

Author: Benzinga Newsdesk | August 06, 2024 07:18am

"We are encouraged to see the benefits of EO-3021's site-specific conjugation translate clinically, with minimal MMAE-associated toxicities observed in our Phase 1 trial. Coupled with the promising anti-tumor activity reported in patients with gastric or GEJ cancer, the data suggest that EO-3021 is a potential best-in-class Claudin 18.2 antibody drug conjugate. We look forward to advancing into monotherapy dose expansion and initiating our combination cohorts in the months ahead, as well as reporting additional data from our ongoing trial in the first half of 2025."

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