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Amylyx Pharmaceuticals Announces Publication Of Data From The Phase 2 PEGASUS Trial Showing The Effects Of AMX0035 On Cerebrospinal Fluid Biomarkers Of Core Alzheimer's Disease Pathology And Neurodegeneration

Author: Benzinga Newsdesk | August 12, 2024 09:06am

- Findings from exploratory analysis of the PEGASUS trial provide preliminary evidence that AMX0035 engages multiple pathological pathways related to neurodegeneration, including tau

Amylyx Pharmaceuticals, Inc. (NASDAQ:AMLX) ("Amylyx" or the "Company") today announced the publication of exploratory analyses on cerebrospinal fluid (CSF) biomarkers from participants with Alzheimer's disease (AD) from the Phase 2 PEGASUS trial. Data analyses suggest that treatment with AMX0035 (sodium phenylbutyrate [PB] and taurursodiol [TURSO]) resulted in consistent changes in AD and neurodegeneration CSF biomarkers in participants with a broad range of disease severity. The results were published in the peer-reviewed medical journal Alzheimer's & Dementia: Translational Research & Clinical Interventions, a journal of the Alzheimer's Association.

Posted In: AMLX

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