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Johnson & Johnson Says Dexamethasone Reduces Infusion-Related Reactions In Patients With EGFR-Mutated Non-Small Cell Lung Cancer Treated With Intravenous RYBREVANT

Author: Benzinga Newsdesk | September 10, 2024 05:21pm

The study, which included 40 patients, showed that prophylaxis with 8-mg dexamethasone taken for two days prior to the first infusion met the primary endpoint of incidence of IRRs at Cycle 1 Day 1 (C1D1), with an all-grades IRR rate for IV RYBREVANT® of 22.5 percent.

This represents a three-fold reduction in the incidence of IRRs compared to standard management of IRRs with IV RYBREVANT®, where historic data has observed an all-grades incidence rate of 67.4 percent.

Posted In: JNJ

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