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New all-in-one IVT kit can deliver up to 2X more mRNA and up to 85% lower dsRNA compared to other kits on the market through streamlined mRNA synthesis with efficient capping, increased yield, reduced dsRNA, and enhanced performance
TriLink BioTechnologies® (TriLink®), a Maravai® LifeSciences company (NASDAQ:MRVI), is fueling the future of mRNA research — starting with a significant donation to top academic labs across the U.S. and Europe.
The donation commemorates the launch of TriLink's first mRNA synthesis kit featuring CleanCap® capping technology, an all-in-one kit with its innovative products in one box at a competitive price. Seven academic institutions will receive ten kits each that can yield up to a combined 250mg of capped mRNAs, enabling and encouraging further discovery and development in the field of mRNA-based medicine.
Labs in academic institutions, such as those listed below, have gratefully accepted the kits donated by TriLink to drive progress in RNA therapeutics and build a strong future for the field.
The new in vitro transcription (IVT) kit will simplify mRNA synthesis and elevate IVT by leveraging TriLink's high-performing products where users can expect up to 2X more mRNA yield and up to 85% lower dsRNA compared to other kits on the market. The IVT kit components include:
"This launch brings together a powerful suite of novel IVT components that reflect TriLink's years of experience and innovation in mRNA synthesis," shared Justin Barbosa, Vice President & General Manager of TriLink Discovery. "By offering all these components in a single kit, we're simplifying researcher workflow and accelerating discovery. The addition of CleanScript IVT optimization also ensures our customers can generate more high-quality mRNA per reaction — maximizing both efficiency and performance."
The kit comes ready to use and is the only commercially available IVT kit featuring CleanCap AG (3′ OMe), which is a modified version of the original CleanCap AG with over 95% capping efficiency to improve protein expression. CleanCap co-transcriptional capping provides advantages over legacy capping methods of ARCA or enzymatic by streamlining mRNA manufacturing with fewer steps and handling, thereby saving researchers time and resources.
"This is an important product launch, where we are bringing several technology and process improvements to an integrated IVT kit," said Trey Martin, CEO of Maravai. "Today we are also making a statement about our commitment to the future of mRNA science. By donating the first new kits to top academic institutions across the U.S. and Europe, we are investing in the next generation of mRNA innovators and empowering groundbreaking research that could lead to the therapies of tomorrow. We are honored to help our field continue to evolve and improve through new innovations and process improvements."
Posted In: MRVI
