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PETACH TIKVA, Israel, July 15, 2025 (GLOBE NEWSWIRE) -- PolyPid Ltd. (NASDAQ:PYPD) ("PolyPid" or the "Company"), a late-stage biopharma company aiming to improve surgical outcomes, today unveiled its long-acting GLP-1 receptor agonists (glucagon-like peptide-1 RA) delivery platform which aims to subcutaneously release GLP-1 RA for approximately 60 days, significantly longer than current weekly injection regimens. The platform releases GLP-1 in a linear way, overcoming the burst release seen with the current weekly delivered molecules. This discovery has the potential to significantly expand PolyPid's offering to a market which is projected to reach $100 billion by 2030.1
"This recent discovery represents a potential paradigm shift in GLP-1 therapy delivery that could transform patient care in the rapidly expanding diabetes and weight management markets," said Dikla Czaczkes Akselbrad, Chief Executive Officer of PolyPid. "By harnessing our proprietary prolonged-release technology, we aim to provide patients with consistent, therapeutic levels of GLP-1 for approximately 60 days with a single administration, potentially eliminating the need for weekly injections. This new pipeline discovery potentially marks a significant advancement in improving medication adherence and patient outcomes, addressing a critical gap in the treatment of obesity and type 2 diabetes chronic diseases."
PolyPid's proprietary technology is a sophisticated drug delivery system consisting of a polymer-lipid based matrix that creates a protected drug reservoir. This unique matrix architecture enables controlled and continuous drug delivery in the body over a prolonged time (weeks to months) in a single application. The technology has been clinically validated in over 1,000 patients including in two Phase 3 trials with no major safety concern.
Posted In: PYPD
