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UK MHRA Authorizes Rein Therapeutics To Initiate Phase 2 "RENEW" Clinical Trial Of LTI-03, For Idiopathic Pulmonary Fibrosis

Author: Benzinga Newsdesk | August 19, 2025 07:12am

Rein Therapeutics ("Rein") (NASDAQ:RNTX), a biopharmaceutical company advancing a novel pipeline of first-in-class medicines to address significant unmet medical needs in orphan pulmonary and fibrosis indications, today announced that the UK Medicines and Healthcare products Regulatory Agency (MHRA) has authorized the Company to initiate its Phase 2 "RENEW" clinical trial of LTI-03, the Company's lead drug candidate for idiopathic pulmonary fibrosis (IPF).

IPF is a serious, progressive lung disease that affects hundreds of thousands of people worldwide. It scars the lungs, leaving patients short of breath and with limited treatment options. Median survival after diagnosis is just 3–5 years.

Rein's LTI-03 is a first-in-class therapy that is designed to directly target fibrosis while also protecting the lung's ability to regenerate healthy tissue. If successful, it could represent a major breakthrough in how pulmonary fibrosis is treated.

Posted In: RNTX

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