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Xilio Therapeutics Initiates Patient Dosing In Phase 2 Of An Ongoing Phase 1/2 Clinical Trial Evaluating Efarindodekin Alfa As Monotherapy In Patients With Certain Advanced Solid Tumors

Author: Benzinga Newsdesk | September 09, 2025 07:37am

Phase 1 data for efarindodekin alfa (XTX301) demonstrate promising anti-tumor activity in patients with advanced solid tumors

Achievement of milestone extends anticipated cash runway into first quarter of 2027
 

WALTHAM, Mass., Sept. 09, 2025 (GLOBE NEWSWIRE) -- Xilio Therapeutics, Inc. (NASDAQ:XLO), a clinical-stage biotechnology company discovering and developing tumor-activated immuno-oncology therapies for people living with cancer, today announced the initiation of patient dosing in Phase 2 of an ongoing Phase 1/2 clinical trial evaluating efarindodekin alfa (XTX301), a tumor-activated IL-12, as a monotherapy in patients with certain advanced solid tumors. In addition, today Xilio announced the achievement of a $17.5 million development milestone under Xilio's license agreement with Gilead Sciences, Inc. (Gilead) and updated data from the ongoing Phase 1 trial for efarindodekin alfa.

Posted In: XLO

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