Silo Pharma Provides Update On Lead PTSD Candidate, SPC-15, Highlighting Safety And Toxicology Results, Ind-Enabling Studies, And Expanded Patents In The U.S., Australia, And Japan. Company Also Launched A Digital Assets Treasury In August 2025, Acquiring Bitcoin, Ethereum, Solana, And ResearchCoin

Author: Benzinga Newsdesk | October 23, 2025 09:04am

Silo Pharma, Inc. (NASDAQ:SILO) ("Silo" or "the Company), a diversified developmental-stage biopharmaceutical and cryptocurrency treasury company, today announced a comprehensive update detailing progress for lead candidate SPC-15, an intranasal prophylactic treatment for post-traumatic stress disorder (PTSD) and stress-induced anxiety, and key achievements under Silo's new digital assets treasury platform launched in August 2025.

Biopharmaceutical Platform:

Silo is advancing SPC-15, its lead therapeutic candidate, through the final preparations required

prior to submitting an investigational new drug application (IND) to the FDA. Recent milestones in its drug discovery program include:

• Positive bioanalytical and safety/toxicology results for an FDA-requested 7-day large animal safety study of SPC-15.
• Finalizing drug-device study of the formulation-specific microchip-based nasal spray system used for SPC-15 drug delivery.
• Completion of an IND-enabling GLP (Good Laboratory Practice)-compliant toxicology and toxicokinetic study of SPC-15. Data is expected in early 2026.
• Global intellectual property expansion with patents for SPC-15 technology in the U.S., Australia, and Japan. Continuing IP expansion is a core element of Silo's drug development strategy.

Digital Assets Treasury:

Silo launched a digital assets treasury strategy in early August 2025 to participate in the growth and adoption of cryptocurrency and to expand and strengthen the Company's capital resources. The strategy combines staking for yield with a hedged overlay to reduce volatility in portfolio positions while maintaining upside potential.

• Initial cryptocurrency purchases made in September and October in Bitcoin (BTC), Ethereum (ETH), Solana (SOL), and ResearchCoin (RSC).
• Lead crypto strategy advisor, Corwin Yu, appointed for active management of Silo's crypto portfolio targeting multi-chain digital asset growth and decentralized finance (DeFi) integration.
• New Crypto Advisory Board, chaired by Corwin Yu, formed to expand Silo's expert support for cryptocurrency audit and compliance. Two additional members are expected to join before year-end or in early 2026.
• Engaged Fireblocks, an enterprise platform for building blockchain applications and managing digital asset operations, and for providing custody technology services for the institutional crypto treasury platform.

Posted In: SILO