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Johnson & Johnson's New Long-Term 52-Week Data From Phase 3 ICONIC-TOTAL Study Evaluating Icotrokinra Continues To Show Potential With Standout Combination Of Exceptional Skin Clearance And Favorable Safety Profile In Once Daily Pill

Author: Benzinga Newsdesk | October 24, 2025 08:03am

In areas of high impact, 72% of patients with scalp psoriasis and 85% with genital psoriasis treated with icotrokinra achieved site-specific clear or almost clear skin at Week 52 in Phase 3 ICONIC-TOTAL study

67% of patients treated with icotrokinra achieved overall rates of clear or almost clear skin by Week 24, which was maintained through Week 52

Icotrokinra continues to show potential with its standout combination of exceptional skin clearance and favorable safety profile in a once daily pill

SPRING HOUSE, Pa., Oct. 24, 2025 /PRNewswire/ -- Johnson & Johnson (NYSE:JNJ) today announced new long-term 52-week data from the Phase 3 ICONIC-TOTAL studya evaluating icotrokinra, a first-in-class investigational targeted oral peptide that precisely blocks the IL-23 receptor, in adults and pediatric patients 12 years of age and older (adolescents) with plaque psoriasis (PsO) affecting high-impact sites.

Posted In: JNJ

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