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Spyre Therapeutics, Inc. (NASDAQ:SYRE), a clinical-stage biotechnology company pioneering long-acting antibodies and antibody combinations to redefine the standard of care for inflammatory bowel disease ("IBD") and rheumatic diseases, today announced scientific presentations at the ACR Convergence Congress.
"We are excited to share follow-up data out to six months from our Phase 1 study of SPY072, our potential first- and best-in-class anti-TL1A agent in development for rheumatic diseases. The data continue to show SPY072 is well tolerated, has a differentiated PK profile supporting quarterly or twice-yearly dosing, and suppresses free TL1A through 20 weeks at the lowest dose," said Josh Friedman, MD, PhD, SVP of Clinical Development at Spyre. "Additionally, we are pleased to share new preclinical data demonstrating that anti-TL1A antibody treatment meets or exceeds the efficacy of etanercept in a rodent model of collagen-induced arthritis, providing additional validation for our ongoing SKYWAY Phase 2 basket study evaluating SPY072 in rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritis."
Posted In: SYRE
