Apogee Therapeutics Highlights APG333 Phase 1 Results Supporting Combination Development With APG777 For Respiratory Diseases
Author: Benzinga Newsdesk | November 10, 2025 07:13am
Interim Phase 1 results for APG333 exceeded trial objectives, demonstrated a half-life of approximately 55 days, and suppressed key biomarkers for 6 months following a single dose, supporting potential 3- and 6- month dosing
Results support development of a quarterly or less frequently dosed co-formulation of APG273 (APG777+APG333) for respiratory indications
APG333 was well tolerated across all cohorts with doses of up to 1,000 mg